Author: Бекмуродова, У.Р.; Жабборов, А. А.; Султонов, Н.Н.

Annotation: In the International Committee (11.02.2020), the so-called SFRS-COV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) caused an international outbreak of the respiratory disease COVID-19. On May 26, 2020, the World Health Organization reported 5404512 cases of the disease associated with COVID-19, of which 343514 deaths. It turned out that a greater number of deaths in this disease are associated with concomitant diseases. In patients with a severe condition with coronavirus, impaired renal function was observed in many cases, which was the cause of death. On March 11, 2020, due to the rapid spread of the coranavirus, a "pandemic"was declared. On 19.09.2020, 50,872 diseases were detected in Uzbekistan, of which 47,121 (92.7%) were cured, 425 (0.8%) deaths were detected, and 3326 (6.5%) patients were treated. Against the background of COVID-19 disease, there are many causes of impaired kidney function. Doctors from the United States and China say that the number of people with kidney failure among patients infected with coranaviruses has increased dramatically. In hospitals, there is an acute shortage of equipment for hemodialysis, as well as the lack of doctors who could provide medical services to patients of this category. Since the coronavirus is poorly understood, it is impossible to say about the direct effect of the virus on the kidneys. The SARS-cov s protein is similar to the ACE receptors and is 10 times stronger in affinity, so it affects the ACE receptors located in the respiratory epithelium of the alveoli, gastrointestinal tract and kidneys. It can be pointed out that 25% of patients with COVID-19 develop CKD and an increase in the number of deaths is associated with the development of renal failure.

Keywords: Coronavirus infection, pandemic, ACE-receptor, chronic kidney disease, respiratory distress syndrome.

Pages in journal: 270 - 281