Author: Khusainova, Munira Alisherovna; Gafforov, Khudoyor Khudoyberdievich; Uzokov, Jurabek Bakhtiyorovich; Tairova, Zarangis Kamoliddinovna

Annotation: The number of patients with chronic liver diseases of various etiologies is increasing in the population, which lead to the development of cirrhosis, which affects other organs and systems, in particular, the cardiovascular system. The aim of the study was to evaluate changes in the QT interval in patients with cirrhosis of the liver and to identify the relationship with the severity of the hepatic process. Material and methods. The study group included 30 patients with cirrhosis of the liver of various etiologies, hospitalized in the therapeutic department city hospital. The comparison group consisted of 30 patients without cirrhosis of the liver, hospitalized at the same time in the same department. The evaluation of clinical, laboratory and instrumental data of patients with the determination of the duration of the corrected QT interval according to the Bazett formula (QTs) was carried out. Statistical processing was carried out with the determination of the average, the error of the average, the reliability of the differences according to the criterion Student, correlation analysis using Pearson's r-test (Microsoft Excel, 2013). Results and their discussion. Prolongation of the QT interval was found in patients with cirrhosis of the liver of various etiologies. A positive correlation was found between the severity of the Child–Pugh liver cirrhosis class and the magnitude of the QT interval. Conclusions. Prolongation of the QT interval in patients with cirrhosis of the liver can lead to the development of life-threatening arrhythmias and be the cause of sudden death of patients, and therefore it is necessary to regularly monitor electrocardiographic data in this group of patients.

Keywords: cirrhosis of the liver, QT interval, cirrhotic cardiomyopathy.

Pages in journal: 94 - 101