Author: Usanov, S.S.; Teshaev, Sh.J.

Annotation: In humans, the desire to improve the effectiveness of treatment, to help the patient get rid of all the diseases that he has developed, inevitably leads to the prescription of many drugs (medicines), which in turn leads to polypragmass in the patient. Polypharmacy is a serious problem in the healthcare system, since it is clinically manifested by a decrease in the effectiveness of pharmacotherapy and the development of unwanted adverse reactions, as well as a significant increase in healthcare costs. The term "polypharmacy" is often used in the medical literature, but there is no universally accepted definition. For this, comparative parameters of morphometric parameters of the liver of white rats in a normal state and under the action of anti-inflammatory drugs on polypragmass were studied. The aim of the study is to supplement data on morphological and morphometric parameters of liver tissue.

Keywords: polypharmacy, morphometry, morphology, inflammation